I've talked about Blueprint here in the past because I use it here and on konigi. Fans of Drupal and Blueprint will be happy to hear that Ted Serbinski has released a Drupal theme that utilizes the Blueprint CSS Framework. Keep in mind that this is for fixed-width layouts only.

Among the features announced:

• normalizes Drupal’s CSS to be consistent
• properly aggregates all blueprint CSS files into a single file when this setting is enabled
• put scripts at bottom of page for nice performance gains
• flexible layout, from 1 to 3 columns, based on where you configure your blocks to show (left, center, right)
• SEO optimization without the need for heavy modules and additional queries per page
• better forum icons
• improved forum display and performance
• prevents duplicate form submissions with jQuery
• shows the # of comments below a node since Drupal doesn’t do this by default (usability)
• highlight any comments by the author of the node
• adds a “you need to login / register” box below all comments if you can’t add a comment (usability)
• supports conditional comment subjects, if the setting is off it won’t show a chopped off title of the comment
• uses CSSEdit comments for grouping of styles

Download the Blueprint Theme here.